The U.S. market remains in an Uptrend Under Pressure. The S&P 500 and Nasdaq regained their respective 50-
DMA this week, with the S&P 500 now trading within 1% of an all-time high. Despite the move, both remain
within consolidation with no real trend yet to develop. We view the 50-DMA as the primary level of near-term
support and resistance at all-time highs. The distribution day count stands at three each with one day expiring
on the S&P 500 next week.
Author: Raj Gupta
O’Neil Health Care Weekly
XLV pulled back 1.17%, outperforming the broader market for a second straight week which has now led to a rise in its
RS line.
Market View
The U.S. market is in an Uptrend Under Pressure. The S&P 500 and Nasdaq broke below their respective 50-
DMA, staging multiple downside reversals to eventually close near the lows of the week. The S&P 500 is nar-
rowly holding above 100-DMA (4,491) support before price support at ~4,430. The Nasdaq is now 7% off
highs and sitting on its 100-DMA (15,082). The next level of price support is ~14,755 before the rising 200-
DMA (14,411). The distribution day count stands at three each with no expiration next week.
O’Neil Health Care Weekly
XLV pulled back 75 bps, outperforming the broader market decline. Despite relatively flat trade, the majority of ideas
continue to bounce back and forth within consolidation, making little progress over the last month.
Market View
The U.S. market remains in a Confirmed Uptrend. The S&P 500 and Nasdaq pulled back sharply this week, with both closing below their respective 21-DMA. The next level of support is September highs at 4,545 and 15,403, respectively, which may also coincide with the rising 50-DMA. The distribution day count remains low at three and one, respectively, with one day expiring on the S&P 500 next week.
O’Neil Health Care Weekly
XLV retraced its prior week gains, remaining in a tight trading range and still lagging the broader market and most other
sectors. To remain constructive on an absolute basis, we need to see the 50-DMA hold just below $131.
Market View
The U.S. market remains in a Confirmed Uptrend. The S&P 500 and Nasdaq are trading at or near all-time
highs and above 10- and 21-DMA support. The distribution day count remains low at three and one, respec-
tively, with one day expiring on the Nasdaq next week.
IQVIA Holdings
Key points from this report:
- Buy IQVIA: The stock is breaking out from a 10-week flat base in heavy volume into all-time highs.
- Upbeat medium-term outlook: On November 16, the company hosted its investor day and announced a new medium-term outlook through 2025. Revenue, EBITDA, and EPS are expected to grow 11%, 12%, and at a double-digit CAGR through 2025, respectively. Consensus expects 8–10% revenue growth and double-digit earnings growth. 2022 guidance assumes revenue and earnings growth of 8% and 13%, respectively, which is likely conservative given that this is their initial guide.
- Strong backlog: TAM of $67B: New clinical trials are up 23% versus 2020 and 13% above 2019 levels, with 85% of sites now accessible. The global CRO target opportunity is expected to have a 6% CAGR through 2025 to reach $67B. IQVIA has a backlog of $24.4B (+13% y/y), of which $6.9B is expected to convert to revenue in the next 12 months.
- Dominant position in the $130B addressable healthcare information market: IQVIA estimates the total addressable market for healthcare information and technology enabled commercial operations is worth $130B. IQVIA has one of the world’s largest and most comprehensive collections of healthcare information. This database sharpens IQVIA’s competitive edge to win large contracts at premium pricing.
- Next catalyst: Q4 results are expected in February 2022.
O’Neil Health Care Weekly
XLV gained 72bps on the week, holding steady just above its 50-DMA. Overall, the sector continues to lag the broader
market over the last few weeks due to multiple crosscurrents mostly surrounding positive data from Covid antiviral pills.
IPO Rewind
Winners (annualized gain of 30% or greater)
• Median market cap at IPO was 38% higher than the median market cap of losers.
• Median revenue growth was similar to losers a year before IPO. However, the revenue growth decline is less than losers.
• Two-thirds of winners were losing money a year before IPO, but nearly two-thirds are improving toward profitability after the IPO.